EP-1286: Does dose-escalated neo-adjuvant radiotherapy improve pathological response in rectal cancers?

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Image guided dose escalated prostate radiotherapy: still room to improve

BACKGROUND Prostate radiotherapy (RT) dose escalation has been reported to result in improved biochemical control at the cost of greater late toxicity. We report on the application of 79.8 Gy in 42 fractions of prostate image guided RT (IGRT). The primary objective was to assess 5-year biochemical control and potential prognostic factors by the Phoenix definition. Secondary endpoints included a...

متن کامل

Does setup on rectal wall improve rectal cancer boost radiotherapy?

BACKGROUND Rectal cancer patients that show a pathological complete response (pCR) after neo-adjuvant chemo-radiotherapy, have better prognosis. To increase pCR rates several studies escalate the tumor irradiation dose. However, due to lacking tumor contrast on online imaging techniques, no direct tumor setup can be performed and large boost margins are needed to ensure tumor coverage. The purp...

متن کامل

The effect of Rectal Retractor, a rectal protector on rectal dose in radical prostate radiotherapy

Introduction: The close proximity of the rectum tissue to the prostate gland results in rectal toxicity during prostate radiotherapy. Rectal Retractor (RR) is a rectal displacement technique that inserts into the rectum, as a result, the lateral and dorsal part of the rectal wall push away from high dose areas. The aim of this study was to investigate the dosimetric consequence...

متن کامل

Does response to neo-adjuvant chemotherapy impact breast reconstruction?

Neo-adjuvant chemotherapy (NAC) is administered in breast cancer treatment for downstaging of disease. Here, we determined the impact of response to NAC on breast reconstruction uptake. A prospective NAC and mastectomy database with or without reconstruction were reviewed with IRB approval. Univariable analyses were conducted using Kruskal-Wallis or Fisher's exact tests. Multivariable logistic ...

متن کامل

Oxaliplatin-based Neo-adjuvant Concurrent Chemo-radiotherapy in Treating Locally Advanced Lower Rectal Cancer

Taiwan and is a major cause of morbidity and mortality all over the world. Lower advanced rectal cancer, a challenge for surgeons, is problematic. Surgical therapy for rectal cancer has evolved since Ernest Miles first described the abdominoperineal resection in 1908. By the 1920s, he had reduced the recurrence rate from almost 100% to approximately 30%, thus ensuring this technique was the gol...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Radiotherapy and Oncology

سال: 2016

ISSN: 0167-8140

DOI: 10.1016/s0167-8140(16)32536-1